Argireline Review 2018-Benefits & Side Effects (Updated July 2019)

Argireline Overview

If you are trying to add various products into your skin care kit that can fight against aging signs then Argireline can be considered as an ideal ingredient for you. Many popular anti-aging topical creams and serums contain this ingredient which is also known as acetyl hexapeptide-3. The effects of this peptide ingredient are just like the effects of Botox for a short time. It helps in preventing crow’s feet and frown lines formed with time in certain areas by slackening their muscles. Many users of this peptide believe that it is very effective for combating the effects of wrinkles and fine lines. But before you start using this skin care ingredient you should have brief information about its working and side effects on your skin.

Introduction with Argireline

Argireline also was known as Acetyl hexapeptide-3 or acetyl hexapeptide-8 is a neuropeptide, one of many peptides often found in various skin care products. It is often used for relaxing muscles especially in the skin care products that are made for reducing the signs of aging. It is a synthetic peptide that works very closely to injectable protein like Botox, which is used by cosmetic surgeons and dermatologists to paralyze certain facial muscles to control their movements. But it does not paralyze facial muscles like Botox as it only restricts their contractions. In this way, it is different from other peptides that are used to communicate with healthy skin cells to increase their healing ability. So, for this reason, this peptide has very few side effects even if it offers nearly the same results as that of injectable toxic peptides. So, Argireline is found in various over-the-counter products even if it is from the line of products like Botox.

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Working of Argireline

Being from the sequence of shortened peptides like Botox, Argireline or Acetyl hexapeptide-3 works similarly on the connections of muscle-to-nerve. It blocks the signals emitted by nerves to the muscles so that affected muscles cannot contract for some time and help in softening and relaxing the wrinkles. In this way it is used on wrinkles, expression lines, crow’s feet, frown lines and forehead lines caused by gravity and sun damage, like Botox, to relax their muscles.

The working of Argireline is based on chemistry as it is made up of peptides, chains of amino acids, which can affect the working of your body cells. Argireline is absorbed into your body when it is applied to the skin. The chemical composition of the cream causes the mild contraction to the facial muscles to diminish the appearance of wrinkles. It can also smooth out fine lines appearing with your increasing age. In some cases, users of Argireline cream or serum experience reduction in wrinkles and fine lines up to 30 percent depending upon the effectiveness of the cream. If you are looking for a product to get rid of the signs and symptoms of aging then you should go for a product containing Argireline without thinking about anything else.

Science behind Argireline

The effectiveness of acetyl hexapeptide-3 or argireline depends upon the type of skin of every individual user. According to various published reports, after using the creams containing argireline some people may experience a reduction in their wrinkles by about 30% within 30 days due to the presence of topically-applied acetyl hexapeptide-3 or argireline with 10% concentration. According to another study, 30% reduction in wrinkles was observed when it was injected into the skin like Botox.

On the contrary, some unlucky people could not get the desired results after using argireline based products consistently. The researchers have shown the possibility of diffusion of this ingredient through thin skins like that of elderly people as it may not work effectively through the thicker skin of youngsters. Some are of the view that it may not reach the crucial connections of nerves and muscles by diffusing through the upper layers of the skin as it shows effective results by injecting into the skin like Botox. In this way, these contradictory studies show different results. So, you can know its effect on your skin just by using it honestly on it.

Some Information about Argireline Products

The skin care products containing Argireline are normally available in jars instead of injections like Botox as this peptide is often used in topical serums and creams. It is also used in combination with other peptides in certain cases to restrict the movement of healthy muscles and cells to encourage the creation of new collagen. In some cases, this peptide is also used in neck creams, night creams, and anti-aging moisturizers under the name of acetyl hexapeptide-3 to reduce your wrinkles while sleeping.

You should consult your cosmetic surgeon or dermatologist to know right skin care product for you if you have never used products containing argireline and are worried about their side effects on your skin. You should also consult your doctor to know the interaction of the peptide you have selected with the medications you are already taking.

On the whole, argireline does not have side effects like that of other peptides like glycolic acid or retinol still it is necessary to be careful while using the tropical serums or creams containing argireline as their main ingredient.

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How to Use Argireline

After knowing some things about argireline it is necessary to know how to use the skin care products containing it. Basically, you should follow the instructions provided on the packaging of the argireline based anti-aging serum or cream but you should also follow certain steps to get the best results. You should apply it in the morning after cleansing and toning your skin if you have selected one to use in the daytime. You should apply it specifically to the areas where you want to control your crow’s feet, forehead line or wrinkles. You should apply these creams or serums carefully around your eyes even if they are harmless for them. Moreover, you should apply these products carefully on other body parts unless you experience any kind of side effects.

Side Effects of Argireline 

Though any authentic information about the side effects of this peptide is not available till date still its long-term use can cause brain fog, as per the experiences of many users. Though its side effects can be of mild nature they can become noticeable if not cared properly. If you experience some side effect after using these creams on daily basis then you should stop using them unless their effects subside. You should also consult your doctor if the side effects of these products persist even after stopping their use.

Is Argireline Safe?

Though argireline or acetyl hexapeptide-3 in topical creams and serums slows down the neurotransmitter neuroepinephrine temporarily like Botox if the topical cream you are using contains the most concentrated dose of acetyl hexapeptide-3 then it should not remain on your skin for more than 8 hours. In case it is used with injectable Botox to stimulate the production of collagen for stretching the skin to increase its firmness or to stimulate fillers then it should be treated properly to avoid any skin problem later on.

Is Argireline Right for You?

Plastic surgery cannot be used by everyone to remove wrinkles and fine lines to regain youthfulness even if he/she can afford its hefty cost. Other reasons to avoid the surgery include the risks involved with it along with painful recovery time. So to avoid such inconveniences many skin care products have been introduced by skin care industry to use them at home to get more effective results without the risks of surgery. The topical serums and creams containing argireline or acetyl hexapeptide-3 are among those products which you can use to get rid of your fine lines and wrinkles. Though these products work like Botox still they are much different from this injectable product.

Who Can Use Argireline Products?

The peptide compounds in argireline and Botox injections work similarly due to their similar nature. The only difference between them is that to reach the lower layer of the skin Botox is injected whereas argireline can be applied topically by including it in topical serums and creams. People with thick skin may not experience the same results as the people with thin skin as it does not penetrate deeply into the skin. Your skin normally becomes thin and susceptible to wrinkles as you age. In this condition, you should apply argireline cream or serum on the spots where it can be absorbed easily. You can also know your eligibility for these products by consulting your dermatologist or cosmetic surgeon about your aesthetic needs.

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Where to Apply Argireline?

Argireline based topical creams or serums should be applied on your neck or face to remove wrinkles but some people also use them around their eyes, mouth, and forehead to get rid of their crow’s feet, smile line or forehead lines. In this way, you can apply this peptide wherever you spot aging signs like under your chin or close to your mouth as these are ideal products for regaining youthfulness. In order to even everything on their face, some people apply it thoroughly on their entire face.

Is Argireline A Natural Product?

Argireline is not a toxin like Botox as it is derived from plants. This is the best option for you if you want to use natural products at a reasonable price to regain your youthful appearance. Its effectiveness like Botox is an additional benefit for you.

Does Argireline Fix Problem Permanently?

Argireline based topical creams or serums do not provide permanent results like most of the topical anti-aging solutions. Though its effect does not last long in some cases it can stay longer than the results of injectable Botox. You can expect permanent result only after surgery. Still, you can maintain your fresh, rejuvenated and youthful skin by using these peptide products regularly. The frequency of using these products depends upon your skin type and the quality of products you are using. In order to get the best results you should follow the instructions provided on the packaging of the topical cream or serum.

Which Products Are The Best?

In order to choose the most effective argireline products, you should go for one containing this ingredient in higher concentration. 10% to 20% concentration of this peptide in such products is recommended by most of the dermatologists and cosmetic physicians to get the best results.

Where Can You Buy Argireline Products?

You can find a wide variety of products online claiming to contain argireline, if you spend some time to search on the internet. Though most of them can be genuine products still you should talk to your doctor or skin care expert before starting to use any of them. While talking to your doctor you should tell him about the medications and treatments you are on so that he can guide you about the possibilities of interactions with your existing line of treatment as these products are not one of the moisturizing creams you use in daily routine.

As the creams containing this peptide help in defying your real age without any kind of surgery or injection of Botox so they are gaining popularity day by day. These creams and serums can not only reduce your wrinkles and fine lines but some of their combinations can also produce more collagens by stimulating your body due to the inclusion of some additional peptide compounds. You can effectively reduce your wrinkles by using argireline products in combination with the products that can invigorate your skin with time. You can see their effect on your aging signs instantly after using them as well as their long-term effect also.

Bottom Line

Argireline or Acetyl hexapeptide 3 is a peptide that freezes your nerve-to-muscle connections like Botox so that you can relax the muscles around fine lines and wrinkles like crow’s feet, forehead lines and frown lines by using them regularly. The effectiveness of these products can be different for different individuals. According to various studies, it can reduce wrinkles effectively up to 30% by using it for 30 days regularly. But in some cases, it can reduce wrinkles even less than 10% by using them for the same time period. The main reason behind this difference can be the difference in absorption of acetyl hexapeptide-3 by their skins.

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