Matrixyl Review 2018- Benefits & Side Effects (Updated July 2019)

What is Matrixyl ?

Matrixyl has evolved as a very popular brand name that acts as an effective supplement to enable the epidermis to produce larger levels of elastin and collagen. Due to this stimulating effect as a result of using the product, the skin gets the power to repair the aging and sun-damaged skin. The major ingredients that are being used in this particular product are two peptides. The peptides are particularly a group of amino acids which are effectively linked together in order to form a short chain. The most popular variant of Matrixyl is Matrixyl 3000. This product has the peptide named palmitoyl-tetrapeptide-7. This peptide is very effective in the process of repairing the DNA of the skin and sometimes reinvigorating the DNA of the skin. This very well facilitates the collagen production. The figure “3000” is a great indication if the more improved Matrixyl product which is prepared out of new peptides namely palmitoyl-tripeptide and palmitoyl-oligopeptide. This new improved Matrixyl has proved to be very effective, potent and long-lasting.

Research on the product

Sederma is the company which had conducted the initial research on Matrixyl. This is the same company which is the manufacturer of the line of products from Procter and Gamble. Sederma also manufactured the popular brand “Olay”. It was way back in the year 2011 when Professor Lan Hamley and his team of researchers were working in the Department of Chemistry at the University of Reading-based out in the UK. They have conducted certain researchers with the aim of finding the possibilities of the healing wounds with the help of collagen. Their team after the researchers have found out that the presence of the aforementioned ingredients in a product can have very positive effects on the collagen’s repair process. So, be it any skincare product, if there is the presence of any kind of peptide in it then it will certainly help in improving the effects on the skin. All this is possible due to the restorative characteristics of collagen.

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How does Matrixyl work?

The original formula of Matrixyl was itself very effective and then the improved version of Matrixyl 3000 has proved to be even more effective.

This is to be first mentioned that the primary ingredients of Matrixyl are the peptides. There are several skin care products which have flooded the market and boast of using peptides for best results but there are very fewer products which mention which particular peptide is actually included in their formula. But Matrixyl stands out from all such products. It clearly mentions that it uses specific peptide called the palmitoyl pentapeptide 3. This particular peptide is very effective in stimulating the process of collagen synthesis. This, in turn, helps very well in skin repair and also an anti-aging formula for the skin.

Matrixyl’s formula was first prepared by Professor Maquart. He was the one who has published an article that talked about the effective use of matrices. In that, he stated that the matrikines are nothing else but a specific kind of peptide which helps in the reducing of the aging effects.

Now the new and improved version of Matrixyl is Matrixyl 3000. Here is a brief discussion of how Matrixyl 3000 works.

Matrixyl 3000 works with two major peptides namely the palmitoyl-oligopeptide and palmitoyl-tripeptide. The creators of this product state that these two peptides very well work synergistically to produce the best possible results. As per the human physiology, whenever there is a breaking down process of collagen, then there is an instant response that there is a need to produce more collage and also elastin.


Matrixyl is a product which has been specifically designed to fix the issues of the aging skin especially on the face as well as on the neck. This product when used regularly, there would be a visible regeneration of the skin cells which would, in turn, reduce the issues that are created due to aging and sun damage. As recommended by the experts, Matrixyl works really well when used twice daily as a part of skin care regimen. The daily usage of Matrixyl will help you in looking younger by improving the texture & tone of your skin. Once Matrixyl is being used regularly, you will see visible differences like less lined, clearer and radiant skin. The collagen level in Matrixyl is high which ensures the epidermis of the skin to look younger plumper, less lined and completely refreshed.

Short-term Benefits of using Matrixyl 

It contains peptides and using this product very effectively stimulate the production of collagen in the epidermis. This will in turn very effectively remove the wrinkles and fine lines from your face. These effects are implemented for a short term and once the serum is washed off from the face, then the effects also vanish. Again the re-application of the product will increase the overall duration of the visible beneficial effects. This is a very well-researched serum and the short-term benefits gained by using this product is time proven.

Long-term Benefits 

Matrixyl is well-designed to have some long-term beneficial effects on the skin when used regularly as a part of skin regimen. Matrixyl contains two peptides which are proved to be synergistic and has the ability to create an effect which is believed to be more powerful than two peptide containing creams used separately. There are chances of irritation on the skin in the short term and dermatitis in the long run when Matrixyl is used continuously. Thus, it is usually not recommended to be used continuously. However, it can be safely re-applied after a short break in the usage of the product.

Recommended Dosages 

This product is a very well-researched one and has been very well formulated in order to generate some very prominent results in increasing the natural levels of collagen. Also, the peptide ingredients that are contained in Matrixyl are chemical in nature rather than being plant-based. These peptides should be used at a maximum of pea size drop daily. Over usage may potentially harm your skin. Also, the peptide formulation in the product is very concentrated one. This is true that the immediate result of using Matrixyl is smooth and satiny skin. But this is to be ensured that too much of cream should not be used in the single go. This may cause reddening of the skin and burning sensation. Also, this is true that if you use the product in larger quantities, it will not increase the effect of the product under such circumstances.

Side effects 

The product can be safely used and is recommended by the experts as there have been no noticeable side-effects either on short-term or on long-term. Although it has been formulated as a low irritant skin cream it can potentially cause dry skin. Some users also experienced rashes while using Matrixyl but this does not happen to all the users. The researchers have done laboratory testing of the formulation used to prepare Matrixyl. In this, the synthetic peptide palmitoyl-tetrapeptide-7 which is a major ingredient of the product is being tested in the laboratory. In the laboratory tests, tetrapeptide-7 has proved to be an agent which causes damage to glycation. Glycation is a process where glucose is linked to proteins in order to create skin’s support. When these links are being damaged, then it results into the saggier epidermis. In such cases, increased dosage of the product is required to see visible results.

Retail Pricing 

The retail prices of the supplement are quite reasonable. You do not need to go out of your budget to purchase this superior quality product. A 35 ml bottle costs $7.95. There can be slight variations in the prices depending on the fact from where you purchase the product. This pure lotion of the product is preferably mixed with rosehip oil in the ratio of 3:5 and then it can be safely used.

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The Reviews from the various regular users of Matrixyl 

Matrixyl has recorded several positive reviews and is now positioned in the market as one of the competitive and popular beauty product. There are several users who have stated that this product has become a necessity in their daily skin care regimen. Also reviews from users’ state that the regular usage of the product has given her baby smooth skin. It also has made her skin firmer and wrinkles from her skin have vanished in few days of regular use. Especially the wrinkles around the eyes and mouth which are very stubborn are gone on regular usage of Matrixyl. The overall rating of the product in Amazon is 4 out of 5 stars which prove that the product is really popular among the users. This kind of great rating in a prominent e-commerce portal like Amazon has also created a great hype for the product.

My reviews on Matrixyl 

My personal reviews after using the product is that is a very effective beauty product which provides natural benefit to the skin. The product is seldom advertised and it is a relatively inexpensive product. This product has gone well with several users and it is very well-reviewed in several online portals. It is being owned by famous company L’Oreal and the company also invests in the research for the development of this product. This is indeed a synthetic peptide serum and has a tendency to dry up the skin. So, for all those users who face this issue, they may use a moisturizer after applying the product.

Matrixyl 3000

  • Although Matrixyl 3000 is an improved version of Matrixyl, the only relationship between them is that they are based out of peptides.
  • There are also several other beauty products available in the market which are made out of peptides. Thus, this is indeed not a huge connection. Peptides are nothing but they are just small fragments of proteins made up off few amino acids. Thus, this is obvious that they are not at all any rare chemical compounds.
  • This is a fact that Matrixyl 3000 was named such in order to popularize the Matrixyl formula. The chemical formulas of Matrixyl and Matrixyl 3000 are different from each other.
  • This is to be remembered that there is a significant difference in the formulas of Matrixyl and Matrixyl 3000. The product is an effective product in increasing the elastin and collagen production.
  • Matrixyl 3000, on the other hand, has had strong anti-aging properties.
  • If compared, Matrixyl 3000 is superior to the original product.

Purchasing Matrixyl 

The product can be purchased as a significant part of anti-aging treatment for daily usage.

Also, it is possible that you can purchase this solution and then able to create a formula all by yourself. You can potentially combine it with a moisturizer and create it as a strong anti-aging lotion. The company Sederma is the manufacturer of the product and the company recommends using the lotion in a concentration of 3% to 8%.

Some of the prominent characteristics of the product are:

  • Suggested to be used at a concentration of 3% to 8%
  • The appearance of this product is opalescent gel
  • It is water soluble
  • It is recommended to be used at 39.2 degrees Fahrenheit.

Final Words

The product is a well-proven and safe skin care product containing peptides. Each one of us becomes conscious about our skin with the increasing age. There are fine lines and wrinkles that starts appearing with increasing age. In order to get rid of such issues, it is necessary to use a product which helps us to get rid of such issues very potentially. Matrixyl is one such product which has been used by several users as a part of their skin care regimen.

It is not at all wise to fill up your dressing table with the bulk of skin care products. Instead, it is beneficial if one effective product is used. If you can very well identify the issues in your skin, then it becomes relatively easier to choose the right product that suits your skin. For all those who are looking for effective anti-aging solutions, Matrixyl is a product that you can blindly trust. But it is important at the same time that you are aware of the right usage instructions or else it may potentially harm your skin.

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