Modafinil Review 2018- Pro’s & Con’s (Updated July 2019)

 What is Modafinil?

Modafinil is a drug that is usually prescribed for people to treat daytime sleepiness and fatigue.  It is a very reliable drug that promotes wakefulness and alertness and has been used illicitly as a cognitive enhancer in highly competitive environments such as workplaces and even universities among others.

This drug is an FDA-approved stimulant that is used for chronic fatigue, excessive daytime sleepiness (known as narcolepsy), obstructive cessation of breathing(known as apnoea) during sleep, and also shift work disorders. Modafinil produces reliable and safe similarity effects, and it has significantly less abuse potential than other stimulants such as amphetamines. This drug is classified by the FDA as only available under prescription which helps reduce drug abuse by individuals.

Modafinil is also used by astronauts to combat fatigue, improve focus, and help adjust circadian rhythm in an artificial lighting environment.

Many reliable survey studies have found that modafinil is often illicitly used and popular within competitive work or study environments. Studies have shown that up to 1 in 5 students had used a stimulant to improve their focus at one point in time.

Allergy and hypersensitivity are the only side effects of the drug, It is highly advised that it is important to consult a physician  before using the drug, This is because problems may arise for people who are sensitive to components of the tablets, to some people modafinil may impair the metabolism of the drug when ingesting it and people with various cardiovascular problems are also advised not to take the medicine without consulting a doctor. Therefore,  caution is to be highly observed.

Modafinil is sold worldwide under different names, some of the names are: Alertec, Alertex, Altasomil, Aspendos, Forcilin, Intensit, Mentix, Modafinil, Modafinilo, Modalert, Modanil, Modasomil, Modvigil, Modiodal, Modiwake, Movigil, Provigil, Resotyl, Stavigile, Vigia, Vigicer, Vigil, Vigimax, Wakelert and Zalux among other names.

This drug has been regularized as a doping agent, and this has made it to be controversial in the sporting world.  the world anti-doping agency (WADA) modafinil is one of the banned substances. The Agency added modafinil to its list of prohibited substances on August 3, 2004, ten days before the start of the 2004 summer Olympics.

Research has found that modafinil and modafinil may slightly reduce negative symptoms in people who are suffering from acute schizophrenia, although it does not appear useful for people with the condition who are stable. Among medications demonstrated to be effective for reducing negative symptoms in combination with antipsychotics, modafinil and armodafinil are among the least power in being effective.

Features of Modafinil

It is a drug that promotes wakefulness and it is made for oral administration. Modafinil is a racemic compound. The chemical name for Modafinil is 2-[(diphenylmethyl) sulfinyl] acetamide. The molecular formula is C15H15NO2S and the molecular weight is usually 273.35.

Modafinil is a white to almost white, crystalline powder that is practically insoluble in water and cyclohexane. It is sparingly to slightly soluble in methanol and acetone.

Modafinil tablets are usually in 100 mg or 200 mg. It has the following inactive ingredients: croscarmellose sodium, lactose monohydrate, magnesium stearate, microcrystalline cellulose, povidone, and pregelatinized starch.

The difference between Modafinil and Other Drugs are as Follows :

Modafinil vs. Amphetamines

The study shows that the product and amphetamines produced similar results in improving cognitive function, fatigue, and mood during A period where a person has been having sleep deprivation.

Some other research shows that modafinil produced overconfidence and overestimation of a person’s own cognitive abilities. While modafinil disrupted one’s self-monitoring cognitive performance, people who were given amphetamine performed accurately when self-monitoring their confidence.

However, research shows that amphetamines are capable of increasing anxiety levels, while modafinil is not.

While modafinil has much lower abuse potential, amphetamines, on the other hand, increase dopamine levels across the brain to a greater extent. For this reason, addiction to prescription of amphetamines is very possible.

Modafinil vs. Caffeine

A research was conducted between the two drugs, the study showed that modafinil, similar to caffeine, did not produce euphoria and less self-well-being compared to amphetamine. Amphetamine also increased anxiety and blood pressure levels more than caffeine and modafinil in patients.

The study showed that caffeine was also not able to sustain alertness awareness during sleep-deprivation studies. In a 48-subject study using a placebo, caffeine, modafinil, and amphetamine, modafinil scored better than caffeine in improving fatigue in patients.

Modafinil vs. Methylphenidate

Methylphenidate is a drug which is most popularly sold as Ritalin; the drug is similar to the product regarding its cognitive enhancing properties. Although research shows that therapeutic doses of methylphenidate do not produce addiction, higher doses could cause euphoria and dependence is often used by people as compared to modafinil.


Benefits of Using Modafinil

Multiple studies have shown that the substance significantly improves emotional processing, such as recognition of facial expressions. It also reduces anxiety, as well as decreased anger-hostility on users.

This drug is said to improve communication (electrical coupling) between neurons In the brain of the user. Research shows that it prevents the damage or death of neurons due to overactivation of receptors by glutamate (excitatory neurotransmitter) and degeneration of dopamine-releasing neurons in the brain.

It is also said that modafinil significantly increased task enjoyment, well-being, and attention compared to other drugs ingested by users.

Researching has shown that modafinil improves the working memory, even in healthy humans. Modafinil, at 100, 200, and 250 mg, showed significantly better results in memory tasks such as delayed verbal recall, digit span, and visual pattern recognition in users. Modafinil significantly reduces the number of errors in several difficult performance tasks when ingested.

It also improves attention in well-rested individuals, while maintaining wakefulness, memory, and executive functions in sleep-deprived individuals compared to other drugs.

Advantages of Using Modafinil

  • It reduces fatigue in users
  • It helps people deal with various kinds of addictions.
  • It helps to improve ADHD symptoms
  • It improves the processing of speed and accuracy in users when performing some tasks.
  • This drug helps users by enhancing their memories
  • It helps users enjoy the tasks they are doing It also motivates them to continue and at the same time giving them confidence.
  • It helps users to improve their athletic performances and we’ll as their reaction time when performing sporting activities.


Disadvantages of Using Modafinil

People who use this drug may experience side effects such as fever, sore throat, headache, and vomiting with a severe blistering, peeling, and red skin rash; bruising and/ or bleeding, severe tingling, numbness, pain, muscle weakness. People should be aware of these effects before taking the drug.

  • The drug may cause hallucinations, unusual thoughts or behavior
  • This product may cause depression, anxiety, aggression; or chest pain, and uneven heartbeats.
  • Less serious side effects may include: a headache, dizziness; feeling nervous or agitated; nausea, diarrhea; trouble sleeping (insomnia); or dry mouth.
  • This drug can only be used by people who have a prescription from a physician.
  • The drug cannot be used by athletes unless they wish to be disqualified from participating in the sport.


How to use this Product

  • When purchasing it from the pharmacy, it comes with a medication guide that provides the user with the necessary information on how to use it. The user needs to read it carefully before starting to ingest it.
  • This medicine is meant to be ingested orally, therefore; the user needs to do so under the direction of a medical practitioner.
  • If the user skips a dose, it is important that they don’t take two doses at once. The should skip and resume normal dosage in the next session.
  • If the user is using this supplement as a method to fight off shift work sleep disorder (i.e. excessive drowsiness due to irregular work schedule or hours), then they should consider taking the supplement one hour or so before work starts. Reviews of this drug have shown that it is almost impossible to fall asleep within 12 hours of taking this drug, so users should plan accordingly for when to take their dosages.

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Modafinil can benefit many users enhance their abilities or even help them stay awake for longer periods of time. In many countries, a person has to have a prescription for them to acquire it.

When considering purchasing this drug, it is advisable that people should seek medical advice from their physician to be advised further on the risks and benefits.  For those who want to buy it online, they should read the manual for proper guidance.

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